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case western reserve university

CTSC at CWRU
clinical research unitS

 
 

WELCOME TO THE
Clinical Research Units
of the
Clinical and Translational Science Collaborative
at Case Western Reserve University

(Formerly the General Clinical Research Centers)


 

 


The Clinical Research Unit (CRU) component of the Clinical and Translational Science Collaborative (CTSC) at Case Western Reserve University is designed to provide investigators with private and semi-private rooms for the conduct of inpatient and outpatient research protocols for both adult and pediatric research subjects. Procedure rooms, a metabolic kitchen supported by a research dietitian, a core chemistry laboratory, a sample processing area, a Human Performance Laboratory, and an array of highly specialized personnel with diverse skills are available to facilitate successful completion of investigators’ protocols. CRU personnel are available to provide expert support in biostatistics, informatics, and specialized laboratory techniques to assist with project design as well as implementation.

The CRUs are located at University Hospitals Case Medical Center (UHCMC), the Cleveland Clinic Foundation (CCF) and MetroHealth Medical Center (MHMC).  Satellite Clinical Research Units are being developed at University Hospitals Bedford Medical Center and the Otis Moss Jr University Hospitals Health Center.  In addition, CRUs can provide clinical research support for protocols conducted throughout these medical centers and in community settings.  Plans to develop a recruitment database are also underway.

The CRU is supported by the CWRU School of Medicine Clinical and Translational Science Award from the Division of Research Resources, National Institutes of Health (UL1 RR024989), which is a new consortium to transform how clinical and translational research is conducted, with the goal of enabling researchers to provide new treatments more efficiently and quickly to patients. Resources are available for use by investigators affiliated with Case Western Reserve University, MetroHealth Medical Center, The Cleveland Clinic Foundation and University Hospitals, with NIH or private funding, as well as trainees just beginning their research careers.


Examples of tests, procedures and services available to Investigators through the CTSC-CRU

TESTING / PROCEDURE CAPABILITY

UH CMC

CCF

MHMC

PeaPod– Neonatal and infant body composition assessment

 

 

X

BodPod – adult and child body composition assessment

 

 

X

Dual Energy X-ray Absorptiometry (DEXA) for ages 4 – adult

 

X

Chemotherapy Administration

X

 

X

Pharmacokinetic testing

X

X

X

Investigational Agent trials, including Phase 1 studies

X

X

X

Sleep Monitoring

X

 

 

Flexible endoscopy

X

X

 

Exercise Stress Testing: cycle ergometry or treadmill

 

X

X

Indirect calorimetry

 

X

X

Pulmonary Function Testing

 

X

X

Bronchoscopy

X

X

X

Anthropometric measurements (skinfold thickness and Bio-electrical Impedance Analysis, Plethysmography)

X

X

X

Dynamic testing: e.g.IV and Oral GTT, GFR,  Continuous Insulin Infusion; Glucose/Insulin Clamp Study

X

X

X

ECG

X

X

X

Blood Draw; IV placement capability (on-site and  remote)

X

X

X

Sample processing

X

X

X

Sample storage

X

 

X

Analytical support

X

 

X

Informatics support, e.g. database design

X

X

X

Metabolic Kitchen

X

 

X

Nutrition Data Software for Research  (NDSR)

X

 

 


REQUEST CTSC RESOURCES (Including CRU Requests)
CTSC Request Management System
CRU DOWNLOADS
NIH Specialty Codes
GRANT CITATION

For projects initiated after 9/17/07 using CTSC resources only please use the following citation:

The project described was supported by Grant Number UL1 RR024989 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH) and its contents are solely the responsibility of the authors and do not necessarily represent the official view of NCRR or NIH.